Stat Up becomes Stat Down), Any 'Stat down' pills you take give you a permanent +0.6 Damage Up (Horse pills +1.2), Most other pills spawn a black heart when used, including R U A Wizard?, Amnesia, Bad Trip, ?? The new rooms contain 0-3 Devil Deal Items, 1-3 Black Hearts and random enemies from the Sheol floor, UNLOCK: Unlock this trinket by defeating Mother as Tainted Judas, Opens the door to the Blue Womb, regardless of whether you meet the 30 minute speed timer, Opening Pandora's Box while holding this item will ignore the normal effect and instead spawn 6 item pedestals from random item pools. Once you've beaten Mother once, a door will appear at the starting room in Depths II, which leads to the Mausoleum/Gehenna floors. Enemies are frozen in place while touching the yellow ring, Enemies touching the ring will stay permanently frozen until you move away, except for bosses which only get a temporary freeze effect after touching it, UNLOCK: Unlock this item by defeating Ultra Greedier as The Forgotten, When you pick this item up, the Mysterious Paper trinket is spawned on the ground, UNLOCK: Unlock this item by defeating Boss Rush as The Forgotten, A familiar that flies across the room every few seconds while firing and damages enemies (2x your tear damage), Can also be used like the Boomerang to pick up consumables on the ground, UNLOCK: Unlock this item by defeating ??? chalice, indiana jones, * angel room pool, god room pool, angel room item, bird, white, Every time you use this item it deals 40 damage to all enemies in the room and Isaac also takes damage, The first use per room takes 1 full heart, then 0.5 hearts per use after that, Shields and invincibility effects do not prevent damage when using this item, Using with Isaac's Heart previously prevented you from taking damage, however in Repentance this was fixed, Using this item as The Lost will instantly kill him, even if you have Holy Mantle active, UNLOCK: Unlock this item by beating Satan with Samson, * item room, treasure room, item room pool, razor, straight, edge, barber, bloody, brown, silver, Follows behind Isaac and can be swung back and forth, dealing 5 contact damage per tick to anything it hits, Every time the hairball kills an enemy, it grows in size allowing it to deal more damage, This is one of the items which allows you to transform into Guppy, Moving to a new floor decreases the size of the hairball, * devil pool, devil room pool, devil deal, grey, brown, pile, guppys hairball, guppy hairball, A familiar that mirrors the player's movements and shoots tears directly at Isaac, Abel's tears do 3.5 damage, unless playing as Cain in which case they do 5, REPENTANCE - Abel now has an increased rate of fire, and will mirror to the other side of the room, even if it's off screen. white, red, pink, When used, slows down all enemies in the current room and their projectiles for about 8 seconds, * item room, treasure room, item room pool, hour glass, hourglass, egg timer, sandbrown, glass, A familiar which follows Isaac around and shoots blood tears that deal 5 damage, The tears appear red but have no additional damage, Sister Maggy fires tears at a rate of 1 tear per second, REPENTANCE - Sister Maggy's tear damage has been increased to 5 (from 3.5), to match its original Flash damage, * devil pool, devil room pool, devil deal, item room, treasure room, item room pool, red, dead, baby, Isaac's tears are replaced with a laser that has unlimited range and can only fire at right angles, Lasers travel through enemies but not obstacles in the room, Synergizes with most items that affect how many tears you fire (20/20, Mutant Spider etc.) From the Sacred Heart to the Magic Mushroom and the mighty Brimstone, here are some of the best and strongest items available in The Binding Of Isaac. If the enemy dies while in this state they will drop 1-4 coins, Rainbow poop Dips charm enemies and have a chance to spawn 1/2 a red heart on death. 13 Holy Mantle. Gives a one-time use of the D6 and D20 effects at the same time, When used will cause two of Mom's Hand to come down and grab a random enemy, Grants the Holy Mantle effect for, which will negate your next hit of damage, Tainted Lost starts with this card, and while playing as this character all cards and runes have a 10% chance to turn into a Holy Card, UNLOCK: Unlock this item by defeating Delirium in The Void floor with The Lost. Thanks for this list. If it touches an enemy it breaks and leave a pool on the floor which freezes enemies and deals 8 damage per tick, * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, REPENTANCE - Dead Sea Scrolls now displays the name of the given effect, and can no longer give Kamikaze. romantic things to do in hollywood, fl; where is hollis and nancy homestead located; houses to rent in nashville, tn under $800; middlesboro daily news arrests; top chef 2021 replay; what does malika mean in the bible. For example, an item which usually gives +1 Damage would instead give a small 'all stats up', Stats effected by this item are: Damage, Tears, Range, Speed, When taken with another item which gives an extreme value in a certain stat (e.g. Replacing all 12 containers with broken hearts will kill you instantly. If you get hit while Cursed eye is a solid black colour you are guaranteed to be teleported to another random room on the floor. All your items and consumables are temporarily removed while in the abandoned mine, The room to access Knife Piece 2 only appears if you have Knife Piece 1 already, You can skip pressing the 3 yellow buttons if you have the ability to fly and have 2 bombs to force open the door, When combined with Knife Piece 1, can be used to stab the fleshy door in the Mausoleum II, which then leads to the Corpse floor and the Mother boss, This is a one time use item that teleports you to an alternate floor, which contains every single item in the game, The items are spread between several different rooms all on pedestals. Unlocked from Challenge #25 - Have a Heart, Feels like I'm walking on sunshine! I want to add that almost EVERY tainted character have something interesting added to game after beating mega satan. Repentance introduces many new strong trinkets, but this is the only trinket that can directly help in achieving completion marks by making getting to Hush easier if you're lucky enough to get this. Unlike the regular D6, rerolled items can pick from any item pool, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Eden, When used, Isaac dies and becomes The Lost for the current room. 15 Of The Best Items In The Binding Of Isaac 15 Mutant Spider. While in a Red room, the chances to spawn a Red Room are: 1 Key = 12.5% chance. starting, bloody, white, bandages, lazarus rags, Gives Isaac a full mapping effect, revealing the entire floor and locations of all secret rooms, UNLOCK: Unlock this item by beating Satan with The Lost, * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, The charge time is based on your tears stat. blue, white, triangle, Isaac's tears become large, brown and will penetrate all objects and enemies (piercing + spectral), Despite the increase in tear size, Dead Onion does NOT increase your damage stat. The longer the button is held the faster Gurdy will fling itself across the screen, Deals a fixed amount of damage depending on charge level, at lowest being ~5 and at max being ~20, Lil Gurdy bounces off of enemies and obstacles, A beggar head which floats around the room and picks up any nearby coins. With Keeper's buff of an additional Coin Heart, unlocking this item isn't that difficult compared to what it would have been in AB+. Repentance introduces a whole new mechanic of Red Rooms - extra rooms attached to the current floor. Also, it was free win because i got Polyphemus on it (I think there's an issue with the Armor scaling on her which is why this causes the crash. achievement (complete a victory lap, defeating the lamb boss), Horf! While the item has a chance to do nothing, there is no negative effect from using it. Function: Adds a special Angel room shop at the start of a new floor, Unlock Condition: Defeat Isaac as Jacob and Esau. Counts as 1 of 3 angel items needed towards the Seraphim transformation. from Fireplaces, Gives you a familiar which is a smaller version of the Plum boss, which sprays tears and propels itself around the room, Deals 2 contact damage per tick to enemies, and the tears deal 3 damage each, Deals contact damage to any enemies it runs into, UNLOCK: Unlock this item by beating Baby Plum 10 times, When used, this item calls a friendly version of the Plum boss to fight for you for 10 seconds, It will jump to the nearest enemy, slam on the ground and fire tears around it, then propel itself around the room, dealing contact damage to any enemies it touches before disappearing, It's possible to get a guaranteed spawn of this item by encountering the Baby Plum boss and not damaging her. Each tick of poison damage is equal to your normal tear damage, Some random tears will gain the Rubber Cement effect and become bouncy, Grants +0.25 Speed, +0.75 Range, +0.1 Shot Speed, +0.2 Tears, +0.5 Damage and +1 Luck when Isaac's active item is fully charged, Infinite use items such as Potato Peeler count as charged and provide the bonus from this trinket, Grants +0.5 Speed, +1.5 Range, +0.3 Shot Speed, +0.4 Tears, +1.5 Damage when Isaac's active item is completely uncharged, One-time use items such as Mama Mega count as uncharged and provide the bonus from this trinket, Gives you another secret room on each new floor while held, Does not spawn more than one super secret room, only the normal secret room, *, purple, torn, ripped, paper, page, poster, When you have the same amount of coins, bombs and keys, half consumables turn into their doubled version, This effect works for any number of consumables, including 0 and 99, as long as the count for coins/keys/bombs is equal, Every time you take damage you have a very small chance to spawn a random pedestal item, When the effect triggers, the trinket is destroyed, Every time you take damage you have a very small chance to spawn the Lunch item, which gives +1 HP up, When the effect triggers, this trinket is destroyed, Increases the radius of any creep you produce, While held, any damage taken remove red hearts first, before soul hearts, black hearts and rotten heart damage, While at 1/2 of a red heart, it will begin to remove your other hearts again, UNLOCK: Unlock this item by beating Greedier mode with Eve, The Walnut has a chance to break when taking damage from an explosion. The size resets when leaving the floor, UNLOCK: Unlock this item by defeating The Beast as Tainted Lazarus, A fetus familiar follows Isaac, and upon entering the Boss room on each floor, it will transform into a copy of the boss, This makes bosses a lot harder, however you now get 2 boss item drops, UNLOCK: Unlock this item by defeating Hush as Jacob & Esau, You gain two familiar demons, that stay by Isaac's side and fire shots in the same direction as you, The familiars deal roughly 40% of Isaac's damage, scaling with damage upgrades you get, They sit near and rotate around Isaac depending on which way you're firing tears. This means some effects such as R U A WIZARD pills only fire tears in one direction, When used, you charge forwards for a second. red, bolt, cupid arrow, cupids arrow, When used, fires a high damage laser in a straight line across the room in a similar way to Brimstone, The laser deals damage equal to double your tear damage. The first piece drops by beating the first floor boss within 1 minute then bombing the shadow in the first room. Health down effects still only remove 1 heart, Eve - Whore of Babylon and Dead Bird effects are always active, Samson - Bloody Lust can gain 4 more damage boosts, for a new max total of +14 Damage, Azazel - His beam becomes much wider, no effect on damage. ?, Paralysis, Retro Vision, I'm Excited, While held, gives you an orbital that blocks enemy shots and deals contact damage equal to 3.5 per tick, While the active key is held down, Isaac gains +0.5 Speed and all of your orbitals spin faster and deal more damage, Orbital damage is equal to 1.5 x OrbitalDamage + 6 while this effect is active, On death enemies now fire tears in random directions, which can damage other enemies, The amount of tears created by this effect depends on the total health of the enemy killed. Larry Jr.) it will split them into 2 smaller enemies with half the number of sections they used to have, If the enemy normally has a mechanic that splits it (e.g. Function: Gives access to the Blue Womb no matter the time elapsed, Special interaction with Pandora's Box (consumes both for 6 random items), Unlock Condition: Defeat Isaac, ?? ), UNLOCK: Unlock this trinket by defeating Mother as Tainted Isaac, Causes Item rooms and Shops to appear in the Cathedral, UNLOCK: Unlock this trinket by defeating Isaac, ?? Sales can be randomly applied just like regular shops, The ladder disappears after leaving the starting room, even if you haven't used it yet, In Antibirth this was called Jacob's Ladder, which had to be renamed as Afterbirth+ already had an item with this name, UNLOCK: Unlock this item by defeating Isaac as Jacob & Esau, Permanently shows the location of the boss room on the map, After defeating the shown boss fight, this item will activate a use of the Sun card (full heal and map reveal), fully recharge your active item, remove curses from the floor, gives +3 Damage Up and +1 Luck up for the rest of the floor, Only available inside a Planetarium - a room that has a base 1% chance to appear, which increases by +20% every time you skip an Item Room (Must not enter to count as skipped), In The Void floor it shows a random boss room, which isn't necessarily Delirium's room, Adds one extra secret room and one extra super secret room to each floor. Explosions now only heal Isaac for half of a heart (previously healed a full heart), * item room, treasure room, item room pool, fire, heart, orange, burning, stannis, Makes tears break into 4 smaller tears on impact with anything, which deal half of your damage, * item room, treasure room, item room pool, brown, orange, headless, crickets body, When getting hit, this item has a chance to drop a soul heart or black heart, The chance to spawn a heart is affected by your luck stat and at +22 Luck it will activate 50% of the time, Enemies have a chance to drop half a red heart when killed, Item Pool: Item Room, Devil Room, Curse Room, Demon Beggar, * curse room pool, demon beggar pool, demon judgement pool, devil beggar pool devil pool, devil room pool, devil deal, item room, treasure room, item room pool, gimp mask, the lost item pool, grey, gray, black, An item only found in the secret room pool, * secret room pool, , the lost item pool, purple, black, grey, gray, flower, mtg magic the gathering, vintage, When you take damage, 1-2 coins will drop on the floor, When playing as the Keeper, this item drops 0-1 coins instead, * shop room pool, shop item pool, item room, treasure room, item room pool, pink, oink, Isaac's tears have a 15% chance of causing a fear effect, Feared enemies will run away from Isaac temporarily, The chance to fear enemies is affected by your luck stat and at +85 Luck it will activate every time, * dungeon room, blood challenge room, arena pool, item room, treasure room, item room pool, Items cost 15-30c, trinkets cost 15c, cards/runes cost 6-8c, black/bone hearts 8c, eternal hearts 15c, rotten hearts 5c, UNLOCK: Unlock this item by spending 40+ coins in the same shop, When picked up, this item fully recharges your currently held active item and drops between 2-4 battery pickups. The actual explosion deals flat 60 damage, Pestilence (Green) - Poisons the enemy it attacks, Famine (Brown) - Applies a slowing effect, Death (Black) - Deals x4 damage instead of x2, UNLOCK: Unlock this trinket by defeating Isaac, ?? After taking two hits, the fire will be extinguished, The Book can be held at the same time as another active item. Doing so will cause it to increase in size, and also increase their damage and the damage of the burst tears, Once a tear is fed 5 times, it will immediately burst, Tears in the burst will deal half the damage the main tear would have, Added as part of the Afterbirth+ Booster Pack #4. If you get hit in either of the other 2 states you will not be teleported, The Black Candle item will remove the Cursed Eye's teleportation effect, REPENTANCE - Burst now has 5 shots instead of 4, * secret room pool, item room, treasure room, item room pool, white, circle, pearl, When Isaac's tears hit anything, they leave a green toxic creep on the floor that damages enemies for 1 damage per tick, * item room, treasure room, item room pool, mystery liquid, grey, gray, green, A familar that is attached to Isaac, which will seek out and damage any enemies close by for 3 contact damage, * astrology, astronomy, item room, treasure room, item room pool, blue, glow, A familiar eye that follows Isaac and copies all his tear modifiers/effects, but shoots in random directions, Tears from this familiar deal 75% of Isaac's tear damage, UNLOCK: Unlock this item by beating Boss Rush with Cain, * item room, treasure room, item room pool, eyeball, white, circle, cataract, cains other eye, A familiar fly that can be moved around via use of the arrow keys dealing 2.5 contact damage per tick, similar to the Ludovico Technique's mechanic, UNLOCK: Unlock this item by beating Boss Rush with Blue Baby, * item room, treasure room, item room pool, blue fly, big fly, blue baby's only friend, fat, dead, ?? are now magnetically attracted to Isaac's tears, Can cause some enemies to have unpredictable movement, * item room, treasure room, item room pool, grey, gray, magnet, Tears are now charged up and fired rapidly in a burst of up to 5 shots at once, The amount of tears fired in the charge depends on how long you charge for, The eye has three states, white (not firing), black (first second of charging) and blinking between black and white. UNLOCK: Unlock this item by defeating Isaac as Jacob & Esau. REPENTANCE - Brown Nugget flies now have faster shot speed, and their damage has been increased to 3.5 (from 2). Enemies touching the head don't hurt Isaac, UNLOCK: Unlock this item by defeating Delirium as Tainted Forgotten, Item Pool: Boss Room, Crane Game, Golden Chest, Drops 1 random rune or soul stone when picked up, Item Pool: Shop, Golden Chest, Mom's Chest, Old Chest, Tears have a chance to become a tooth, dealing x3.2 damage, similar to Tough Love, The chance to fire a tooth with this trinket is affected by your Luck stat, At +0 luck you have ~12% chance for this effect to activate, At +9 luck every tear you fire will be a tooth, Chance to spawn half a soul heart when picking up a coin, The chance scales up based on the coin's worth: Penny = 16.66%, Double Penny = 30.5%, Nickel = 59.7%, Dime = 83.3%, UNLOCK: Unlock this trinket by defeating ??? This works with all normal pickups, including cards, runes, chests and trinkets. UNLOCK: Unlock this trinket by defeating Greedier Mode with ??? The item is very hard to unlock, though. e.g. If you have 40 bombs it will spawn 4 x Boom! * boss room pool, boss room item, mr. squeezy, mr squeezy, cobaltstreak, white, brown, red, bow, * boss room pool, boss room item, purple, carton, grape drank, When picked up, spawns 1 red heart, 1 key, 1 bomb, 1 coin, 1 card/rune, 1 pill and 1 trinket, * dungeon room, blood challenge room, arena pool, normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, boss room pool, boss room item, brown, orange, cardboard, Doubles the yield of hearts, coins, bombs and keys that spawn from non-red chests, Item Pool: Shop, Challenge Room, Key Beggar, Mom's Chest, * key master pool, key beggar pool, key judgement pool, , dungeon room, blood challenge room, arena pool, shop room pool, shop item pool, golden, horns, moms key, mom key, Tears have a random chance to charm enemies, Charmed enemies will prioritize attacking other enemies in the room, otherwise they will still attack Isaac, The chance to charm enemies is affected by your luck stat and at +27 Luck it will activate every time, * dungeon room, blood challenge room, arena pool, item room, treasure room, item room pool, Room are: 1 Key = 12.5 % chance spawn 4 x Boom 2 ) broken hearts kill! 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best items to unlock isaac: repentance