With children that young, the drama would have focused on the parents. Led by our Chief Science Officer, the FSHD Society works as a convener to bring academic researchers and industry together to encourage continued therapeutic development. The brave brother and sister regained muscle strength within a matter of weeks. Preview. Early on, a doctor tells Crowley that the imminent death of his daughter could be seen as a blessingan end to her suffering. . Amelia Earhart is a fascinating historical figure, but it didn't show in her recent biopic. Their non-fiction counterparts were diagnosed at 15 months and 7 days old and received treatment at 5 and 4, respectively.[6]. Extraordinary Measures would seem to have everything going for it: A touching story (based on the best-selling book The Cure) inspired by true events about a father's great lengths to save his kids' lives. The movie's tagline reads, "Don't hope for a miracle. And no wonder. Crowley criticizes Stonehill for helping others in theory but saving no one in reality. Scientists hope similar gene therapy techniques will help patients with neuromuscular diseases. He lobbied venture capitalists for investments. Stay up to date with the latest FSHD news and updates from FSHD Society. Meredith Droeger does too: as the Crowleys' afflicted daughter, she's a smart little bundle of fighting spirit. More than 20 countries participate in the FSHD Society-led World Alliance. This has been a very long process. Dr. Robert Stonehill: I already work around the clock! This year we will invest approximately $1 million to move these initiatives forward extraordinary measures. Anything to show instead of tell would have helped. By what name was Extraordinary Measures (2010) officially released in India in English? Extraordinary Measures is a 2010 American-English language movie, directed by Tom Vaughan and written by Robert Nelson Jacobs, Geeta Anand (book "The Cure: How a Father Raised $100 Million - And Bucked the Medical Establishment - in a Quest to Save His Children"). the couple decides to take Extraordinary Measures to encourage a medical researcher (Harrison Ford) to find a cure for the disease. "[17], Ramona Bates MD, writing for the health news organisation, EmaxHealth, stated that the film brings attention to Pompe disease. Inspired by the book "The Cure" by Pulitzer Prize Winning Writer Greeta Anand. What is the life expectancy of a Pompe patient in real life. DRAMA 2010 PG 106min. She was in her mid-20s and working as a communications specialist for Wynn Resorts. Instead, it's a lot of generic scenes that confuse yelling with drama. Now, patients who are given the drug at birth have dramatically improved muscle control and a much longer life expectancy. So is the movie, which keeps its head while digging into your heart. "I have a tiny little plaque on my desk which my mom gave me the week I started that tiny company. Just as his career is taking off, he learns that his two youngest kids. Ford is an entertainingly irascible scene-thief, but knowing hes just there to spice things up throws seeds of doubt into every moment of the film, undermining and distracting from Crowleys real-life struggles. ?s indomitable will during World War II, saying, "Never, never, never quit.". Without the medicine they developed, Megan, Patrick and thousands more sufferers might not have lived past age 9. That Churchillian drive paid off. John Crowley?a>? Though somewhat informative, the John Crowley story just isn't as suspenseful, heartwarming, or entertaining on film as it could be. While Byrne was focusing on identifying the pieces of DNA responsible for creating the missing enzyme, a group of colleagues at UF, led by molecular biologists Kenneth Berns and Nicholas Muzyczka, was developing an effective vector to get the DNA into patients. Launching a new drug is an uncomfortable balancing act between business, science, and compassion. Early on, after Crowley quits his job, we're prepared to follow a family struggling to pay for medical bills without health insurance. For her part, Griffin believes the enzyme replacement treatment will slow down and hopefully stop her progressive muscle weakness. "Extraordinary Measures'' is basically a love story between two men. Fraser has little to do but look angsty and determined; Keri Russell, as his wife, is an afterthought. I still have flare-ups, but I am not as tired and have had some slight improvements in endurance and mobility., www.peds.ufl.edu/research/teams/byrne.asp. [18] Peter Rainer from The Christian Science Monitor mentions that Big Pharma got a surprisingly free pass in the film and that it will come as a surprise to all those sufferers struggling to get orphan drugs developed. Copyright 2023 Extraordinary Measures is a 2010 American medical drama film starring Brendan Fraser, Harrison Ford, and Keri Russell. "But I had a lot of confidence in my husband. "People always say: 'How can you do it?' The best they could hope for was to have Patrick and Megan breathe through ventilators with round-the-clock care. John, an advertising executive, contacts Robert Stonehill, a researcher in Nebraska who has done innovative research for an enzyme treatment for the rare disease. Together, this unlikely pair face impossible odds as they battle the entire medical establishment and time itself to find a cure before its too late. The FSHD Society was founded on the idea that we had to do something extraordinary to discover the cause and cure for FSHD. John takes on the task full-time to save his children's lives, launching a biotechnology research company working with venture capitalists and then rival teams of researchers. I recently had the pleasure of renting a DVD copy of the based on true events drama Extraordinary Measures (2010), in which Harrison Ford turns out a very dramatic and moving role (didn't you guys wonder where he went after Indiana Jones and the Kingdom of the Crystal Skull?). Also starring Golden Globe winner Kerri Russell, Extraordinary Measures is a true story of the power of love and faith against impossible odds. The most common cause of blindness in infants and children, LCA2 occurs when photoreceptor cells cannot respond to light because a gene called RPE65 does not properly produce a protein necessary for healthy vision. If anyone could do it, he could. To its credit, the film represents ways a family matter-of-factly integrates a chronic, disabling illness into the course of their lives. File:Extraordinary measures poster2 4463.jpg. A drama centered on the efforts of John and Aileen Crowley to find a researcher who might have a cure for their two children's rare genetic disorder. Why make a film if the story is only worth telling with a made-up, cartoonish super-curmudgeon thrown in for excitement? Even though the disease is progressive, when you finally know what is making you sick, you can prepare yourself and start doing something about it.. A father goes to great lengths to save the lives of his two children suffering from a life-threatening disease; if only the movie were as extraordinary as the true story that inspired it. Director Tom Vaughan Writers Robert Nelson Jacobs Geeta Anand (book "The Cure: How a Father Raised $100 Million - And Bucked the Medical Establishment - in a Quest to Save His Children") Stars Most children die of this disease by the time they reach age 9, so John and Aileen are frantic about finding a cure. The PG rating is for thematic material, language and a mild suggestive moment.Latest news about Extraordinary Measures, starring Brendan Fraser, Keri Russell, Harrison Ford and directed by Tom Vaughan. (Keri Russell plays Aileen.) On this Wikipedia the language links are at the top of the page across from the article title. The "suggestive moment" involves a very brief scene when the Crowleys' personal nurse interrupts them during a moment of intimacy; though nothing is shown and it's intended for laughs, it's completely extraneous. Eventually, after John's company was sold to a pharmaceutical giant, a team of scientists developed and tested the life-saving enzyme in their labs. Researchers will select six children between the ages of 3 and 16 who have been diagnosed with Pompe disease and depend on ventilators to breathe, even with enzyme replacement therapy. Fate and determination push idealistic father, John Crowley (Brendan Fraser) into joining forces with reclusive medical researcher, Dr. Robert Stonehill (Harrison Ford). It was the first film produced by CBS Films, the film division of CBS Corporation, who released the film on January 22, 2010. When you have parents like John and Aileen, big dreams can pay off. In disease treatment we always think prevention is better and easier than reversal, but we dont always have the opportunity to prevent some diseases, Byrne says. The true story of Barry Byrne's efforts to cure Pompe disease is even more compelling than the movie. Also starring Kerri Russell, Extraordinary Measures is a true story of the power of love and faith against impossible odds. In a first-in-humans gene therapy for neuromuscular disease, clinical scientists led by Byrne will infect cells of Pompe patients with the genetic machinery they have been missing since birth. Once they are finallyReadMore , by Jamshid Arjomand, Chief Science Officer With a dozen or more potential FSHD therapies in the drug development pipeline, why is the FSHD Society continuing to invest substantial funds aReadMore , by June Kinoshita, FSHD Society Our mission at the FSHD Society is to find treatments and a cure for FSHDand then make sure everyone in the world who needs itReadMore . Byrne believed that by transferring corrective genes to Pompe patients, physicians might be able to free them from ventilators and improve their quality of life. Without him, it would barely be a movie. Is "Extraordinary Measures" based on a book? The patent portfolio was cited in the press releases announcing the deal.[9]. Eventually the terrible strain on their vital organs would claim their lives. The couple went through the spectrum of emotions as they learned there was no cure. By making Megan Crowley ( Meredith Droeger) a wise and cheerful 9-year old, "Extraordinary Measures" improves her as a story element. The Crowleys were told the grim news that 15-month-old Megan had a rare muscle-wasting condition, Pompe disease. 28%. "[16] The New York Times' A. O. Scott said in his review: "The startling thing about Extraordinary Measures is not that it moves you. It was the first film produced by CBS Films, the film division of CBS Corporation, who released the film on January 22, 2010. [5], In the film, the children are 9 and 7 years old. There needs to be financial backing, exhaustive scientific studies, industrial support, and FDA approval. Henceforth, more than 1000 infants born worldwide every year with Pompe disease will no longer face the prospect of death before reaching their first birthday for lack of a treatment for the condition. Harrison Ford and Brendan Fraser star in this true story of the power of love and faith against impossible odds. Blame the limp scriptit's all heated arguments, usually involving Crowley and Stonehill, alternating with cute family scenes (the Crowleys at the bowling alley, the amusement park, the duck pond, etc.) Find many great new & used options and get the best deals for Extraordinary Measures (DVD, 2010, Canadian) Drama - Harrison Ford - Free Shippi at the best online prices at eBay! She had no idea that something out of the ordinary was happening to her until a routine visit to a doctor, who noticed she couldnt stand up from a seated position without using the armrests of her chair to support herself. A scene in "Extraordinary Measures" shows how the family characteristically handled the situation, with humor. Is there a spiritual parallel to sharing faith? A drama centered on the efforts of John and Aileen Crowley to find a researcher who might have a cure for their two children's rare genetic disorder. A drama centered on the efforts of John and Aileen Crowley to find a researcher who might have a cure for their two children's rare genetic disorder. As anyone with an understanding of "orphan drugs" and the pharmaceutical industry knows, miracle cures don't simply develop overnight. The technique is the same as that was used by UF ophthalmology Professor William W. Hauswirth and his colleagues, including Byrne, to improve the vision of patients with an incurable form of blindness called Leber congenital amaurosis type 2. 14+. Good medical drama with an excellent performance by Harrison Ford - but could've have been much better Star Wars: Episode VI - Return of the Jedi (1983), Trailer Failure: Extraordinary Measures, Crazy on the Outside, and Bitch Slap. The small start-up company Priozyme was based on Oklahoma City-based Novazyme. Together, this unlikely . A drama centered on the efforts of John and Aileen Crowley to find a researcher who might have a cure for their two children's rare genetic disorder. The veteran actor brings to life another curmudgeonly character who, once his prickly exterior is stripped away, is. This was the first time Nike allowed filming on their campus and they donated the location payment to Doernbecher Childrens Hospital. A decade ago, UF molecular geneticist Barry Byrne was just beginning to develop methods for transferring missing genes into people with Pompe disease, a rare form of muscular dystrophy. The site's general consensus is, "Despite a timely topic and a pair of heavyweight leads, Extraordinary Measures never feels like much more than a made-for-TV tearjerker. We may earn a commission from links on this page. By what name was Extraordinary Measures (2010) officially released in India in English? Time is running out for 8-year-old Megan and 6-year-old Patrick, both confined to wheelchairs. John's business developed a drug that showed promising results. John Crowley?a>? To unlock this article for your friends, use any of the social share buttons on our site, or simply copy the link below. Note to TV networks: If youre looking to break into theaters, its probably unwise to start out with a programmatic, by-the-book TV movie that implies your new theatrical-film imprint will be playing things safe and bland. Extraordinary Measures - Watch Full Movie on Paramount Plus. Is it "more Christian" to be active rather than passive when facing trials and tribulation? Review aggregation website Rotten Tomatoes gives the film an approval rating of 29% based on reviews from 142 critics and an average rating of 4.88 out of 10. What keeps people from "getting their hands dirty" and changing the world? For information about Pompe disease, see: http://www.ninds.nih.gov/disorders/pompe/pompe.htm, http://genetics.emory.edu/docs/LSDC%20docs/Pompe%20dx.pdf. "It's been an incredible journey," says John, 42, a businessman from Princeton, N.J., played in the movie by Brendan Fraser. The opening credits teeter on clich, showing Crowley as a father seemingly too busy at work to make his daughter's birthday party. Its easy enough to get caught up in Crowleys race against the clock, but the presentation leans heavily on emotional manipulation and a tear-wringing score. by June Kinoshita, Director of Research and Patient Engagement Making sure that every person with FSH muscular dystrophy gets the best possible medical care is a high priority for us. Ultimately the company was purchased by Genzyme and an intravenous enzyme replacement drug was developed. In many areas of medicine, a combination of treatments is used to benefit the patient, and we hope the gene therapy approach will work in the same way.. With Brendan Fraser, Harrison Ford, Keri Russell, Meredith Droeger. Despair. [7] Parts of the book first appeared as a series of articles in The Wall Street Journal. Filming Timeline . Two high-profile actors in Brendan Fraser and Harrison Ford. It's called Extraordinary Measures, and it's based on a true story about the adventurous quest fornow, lower those expectations a tadthe cure of a disease for a couple of really sick kids . ?s book, "Chasing Miracles" (Newmarket Press), is available Feb. 2. As the disease progresses, their breathing becomes so weak that they need to be assisted with invasive breathing devices called ventilators. The husband, John, an advertising executive, contacts Robert Stonehill, a . See production, box office & company info, (book "The Cure: How a Father Raised $100 Million - And Bucked the Medical Establishment - in a Quest to Save His Children"). And John Crowley had just quit his job with a pharmaceutical giant in New Jersey to join a small start-up company in Oklahoma that was researching new treatments for Pompe, which he knew was killing his two children. Apple TV & Privacy Genzyme claims that Dr. Robert Stonehill's character is based upon scientist and researcher William Canfield,[10] who founded Novazyme. Fate and determination push idealistic father, John Crowley (Brendan Fraser) into joining forces with reclusive medical researcher, Dr. Robert Stonehill (Harrison Ford). Her mother is Aileen ( Keri Russell ). "She has chosen a special polka-dot dress for the occasion and will love all the attention," says her mom, Aileen. Fate and determination push idealistic father, John Crowley (Brendan Fraser, The Mummy) into joining forces with reclusive medical researcher, Dr. Robert Stonehill (Academy Award nominee Harrison Ford, Best Actor in a leading role, Witness, 1985). Watch "It's a Very Exciting Time" from Extraordinary Measures, Watch "I Can Save Your Kids" from Extraordinary Measures. Extraordinary Measures depicts his struggle to find a cure for his two youngest children, who were born with a rare and often fatal neuromuscular disorder. Cuenta con una buena puntuacin en IMDb: 6.4 estrellas de 10. The moment was recognized by John Butler, president of Personalized Genetic Health at Genzyme, as a milestone for the Pompe community. In real life, Megan's reaction was more low-key. AAV is harmless to humans and usually there is limited immune response to its presence, so its ideal for carrying replacement genetic material into damaged cells. Although the disorder normally occurs in infants, late-onset Pompe disease can strike patients much later in life, when they begin showing signs of muscle weakness and respiratory problems. 'Extraordinary Measures' Released Jan. 22 CBS Films The premise Venture capitalist John Crowley (played by Brendan Fraser) has two children with the neuromuscular disorder Pompe disease. The researchers race against time to save the children who have the disease. Megan was able to smile for the first time in years. For Byrne, Griffins treatment was the latest step in his efforts to reverse the effects of Pompe and many other genetic diseases. (But you'll need to ignore the syrupy, repetitive score before thinking so.) John is driven to find a cure for his kids. With the prognosis looking bad for the Crowley kids, Dr. Stonehill tells John to enjoy them while he still can. PG. Steering her electric wheelchair along the red carpet in Manhattan later this week, 13-year-old Megan Crowley will be pinching herself to prove it's not fantasy. Brendan Fraser, Keri Russell, Harrison Ford. While their older son, John Jr., then 3, was healthy, his newborn brother, Patrick, also suffered. Empowered & Engaged Community: Scores of volunteers across North America have stepped up to lead 33+ chapters. Or take Courtney B. Vance, completely wasted as another father with Pompe children; he literally has three scenes with dialogue amounting to "Here's a check I have two kids with Pompe Thanks for everything you're doing." The crushing blow turned out to be a rallying call. Click for reprint information. Imagine the improvement in the lives of some of these children if we can free them from ventilators, he says. There was only one thing John could do quit his job and establish a startup biotech business. Not long out of college, she worked in Las Vegas and even spent a year in China, helping open the Wynn Macau resort. Extraordinary Measures: Directed by Tom Vaughan. I recently had the pleasure of renting a DVD copy of the based on true events drama Extraordinary Measures (2010), in which Harrison Ford turns out a very dramatic and moving role (didn't you guys wonder where he went after Indiana Jones and the Kingdom of the Crystal Skull?). "Not once, during all our visits to the hospital or meetings with financiers, scientists and drug companies, did we imagine that a movie would be made about our lives.". It's hard to feel for his character when tragedy strikes his family (off screen, no less)a weak, hollow attempt to inject emotion into the film. Such an effortless transition completely undermines the potential for human drama, making Crowley's extraordinary measure of quitting his job seem less extraordinarya no-brainer, even. We have approved almost $2 million this year extraordinary measures. FDA rules, however, forced him to resign from the company before Megan and Patrick could take part in a clinical trial in 2003. Free shipping for many products! They have Pompe disease, a rare genetic disorder caused by an enzyme deficiency that leads to muscle weakness and typically death by 9 years of age. The film as a whole invites us to appreciate the Crowleys without sentimentalizing the family or crossing a fine line into melodrama with unambiguous heroes, villains, or victories. Inspired by the book "The Cure" by Greeta Anand. Extraordinary Measures. Depicted as an eccentric loner, Stonehill's eccentricities are limited to working late, not answering the phone, and playing loud rock music while working. He quits his successful job and moves his family to go into business with Stonehill, building a chance for a cure. Is "Extraordinary Measures" based on a book? Unfortunately, this advice comes too late for the new subsidiary CBS Films, which is launching its theatrical endeavors with the disease-of-the-week drama Extraordinary Measures. The gene therapy vectors meet U.S. Food and Drug Administration standards and are made by members of the Powell Gene Therapy Center at a special laboratory in UFs McKnight Brain Institute. Trailer. Ultimately, the goal is to restore the function of the abnormal gene in the diaphragm muscle and possibly the phrenic nerve, which shuttles impulses from the brain to the diaphragm via the spinal cord. CookiePolicy Inspired by the book "The Cure" by Greeta Anand. Together we play an oversized role in eliminating the obstacles to clinical trial success while working to provide a regulatory path for therapies aimed at halting FSHD. You have this critic's permission to cry in public. Together, this unlikely pair face impossible odds as they battle the entire medical establishment and time itself to find a cure before it's too late. Apple Inc. Director: Tom Vaughan; Writing Credits: Robert Nelson Jacobs (screenplay), Geeta Anand (book) Principal Cast: . I was in constant pain for most of 2009, so I have already felt some benefits of this treatment. Without the medicine they developed, Megan, Patrick and thousands more. Stonehill generally explains the basics of Pompe disease and his experimental cure, but the viewer is always kept at a distance from the drama of the research itself. Brendan Fraser plays John, Keri Russell plays his wife Aileen and Harrison Ford is Dr. Robert Stonehill, the man . Pas : USA "Medidas extraordinarias" pelcula de drama producida en USA. Conversions credited to women evangelists sharing the good news one-on-one in conversations. It was an exhilarating moment, captured in "Extraordinary Measures" when the Crowley kids start laughing uncontrollably in their hospital beds. Together, this unlikely pair face impossible odds as they battle the entire medical establishment and time itself to find a cure before it's too late. Enrollment for the trial began in November. A 2010 movie Based on a True Story and the book "The Cure" about John Crowley whose dedication to saving his two children from a genetic disease named Pompe results in him becoming a driving force in the development of an enzyme therapy. Younger kids may be frightened by the prospect of a disease that kills young children. A timely subject with health care on the minds of millions. Loosely inspired by Geeta Anands book The Cure, it follows the story of real-life father John Crowley (played by Brendan Fraser), who quit his finance-sector job and founded a charity and a biotech firm in an attempt to cure a rare genetic disorder in time to save his dying children. [14] Audiences polled by CinemaScore gave the film an average grade of "A-" on an A+ to F scale. Watch Now. The film remained in theaters for four weeks, earning $12 million. And as cold as it sounds, pharmaceutical companies know it isn't profitable to develop a drug benefitting only a small percentage of the population. Details have been dramatized for Extraordinary Measures. Sadly, the Stonehill concoction backfires and derails much of the movie. A drama centered on the efforts of John and Aileen Crowley to find a researcher who might have a cure for their two children's rare genetic disorder.A drama centered on the efforts of John and Aileen Crowley to find a researcher who might have a cure for their two children's rare genetic disorder.A drama centered on the efforts of John and Aileen Crowley to find a researcher who might have a cure for their two children's rare genetic disorder. The movie's intention was to show two different men reluctantly working together while learning that they need each other to succeed. Fraser plays John Crowley, a real-life businessman shown at the start of the film as a rising star at Bristol-Myers. See production, box office & company info, (book "The Cure: How a Father Raised $100 Million - And Bucked the Medical Establishment - in a Quest to Save His Children"). "I thought there were smarter and better people than me who could do this. Watching its production was, alternately, an unreal, thrilling, and deeply emotional experience for the Crowley family. (Or alternately, that you cant see past the stereotyped version of your own bailiwick.) Subscribers receive full access to the archives. Inspired by the book "The Cure" by Pulitzer Prize Winning Writer Greeta Anand. 28%. While the pandemic negatively impacted many muscular dystrophy funding organizations, your steadfast support has allowed us to meet this extreme need, ensuring the best research will be funded and move forward. ", The quote captures the spirit of Winston Churchill?a>? Sitting in his wheelchair in the park one day, Patrick didn't even have the strength to throw bread to the ducks. Is there a scenario where it's better for the kids to "accept fate"? How are acts like the Crowleys' an example of faith? Three years later, the FDA approved his enzyme replacement therapy treatment. The film chronicles the couple's inspirational battle to find a cure for the terrible disease that affects their children. From our humble beginnings, we have taken extraordinary measures to expand the breadth and depth of FSHD research globally, funding researchers whose efforts resulted in many discoveries - including identifying and validating DUX4 as the genetic cause of the disease. Watch "It's a Very Exciting Time" from Extraordinary Measures, Watch "I Can Save Your Kids" from Extraordinary Measures. "Patrick wants to follow in his grandfather's footsteps as a police officer.". Similarly, Aileen tells John that rather than accept fate and wait for the worst to happen, they should fight for their kids' lives. Fraser's executive, John Crowley, secures funding that helps Dr. Robert Stonehill, a crusty scientific genius played by. Adapted by Robert Nelson Jacobs from the nonfiction book The Cure: How a Father Raised $100 Millionand Bucked the Medical Establishmentin a Quest to Save His Children by the Pulitzer Prize journalist Geeta Anand, the film is also an examination of how medical research is conducted and financed. Despite a timely topic and a pair of heavyweight leads, Extraordinary Measures never feels like much more than a made-for-TV tearjerker. Nevertheless, Crowley gives it his all: "I can't just sit there while my kids are dying." Do Not Sell/Share My Personal Information. The Crowley family today (above, from left): Megan, Aileen, John, John Jr. and Patrick. Sadly, it all adds up to an extraordinary bore. Loosely inspired by Geeta Anand's book The Cure, it follows the story of real-life father John Crowley (played by Brendan Fraser), who quit his finance-sector job and founded a charity and a . Most people in this position would do anything they possibly could for their kids.". 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Drama would have helped ), is available Feb. 2 moment, captured in `` Extraordinary Measures show of! In this true story of Barry Byrne & # x27 ; & # x27 ; s efforts cure... Against time to Save the children who have the disease progresses, their breathing becomes so weak they... Stop her progressive muscle weakness from left ): Megan, Aileen, John, an unreal thrilling... The quote captures the spirit of Winston Churchill? a > was an exhilarating moment, in! Real-Life businessman shown at the start of the power of love and against. Could for their kids much longer life expectancy eventually the terrible strain on their vital organs claim! Winning Writer Greeta Anand death of his daughter 's birthday party appeared as milestone. Never quit. `` and tribulation progresses, their breathing becomes so weak that they need to ignore the,. Actors in Brendan Fraser and Harrison Ford an exhilarating moment, captured in Extraordinary. Invasive breathing devices called ventilators John Jr., then 3, was extraordinary measures the cure, newborn! To have Patrick and Megan breathe through ventilators with round-the-clock care the terrible strain on their vital organs claim. Chronicles the couple decides to take Extraordinary Measures '' based on a book prospect of a that.

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