Item Tags Cannot be obtained and has no use for any other character, Birthright is a Shop item that has unique effects depending on what character you're playing as, This is the item Tainted Blue Baby (???) UNLOCK: Unlock this item by defeating Mother in the Corpse II as Lilith. They also no longer block player attacks or get extinguished by them, UNLOCK: Unlock this item by donating 400 pennies to the Shop, Isaac can now pick up hearts while at full health, which will be stored in the Jar and can be spawned again using the spacebar, Soul hearts and black hearts cannot be stored, If used in a Black heart or Eternal heart super secret room, it will spawn the relevant heart, * shop room pool, shop item pool, the lost item pool, glass. - Turns Isaac invincible for a few seconds (similar to Unicorn Stump). The Binding of Isaac Wiki is a FANDOM Games Community. This works with all normal pickups, including cards, runes, chests and trinkets. Modes Grants a charged shot that fires 14 tears in the same fashion as. with Brimstone you get 4 lasers, Counts as 1 of 3 spider items needed towards the Spider Baby transformation, * item room, treasure room, item room pool, green, black, +2 Damage Up for tears fired from Isaac's left eye, If playing as Cain or you have an item which modifies which eye you fire tears from, each shot has a 50% chance to do +2 Damage, * item room, treasure room, item room pool, poison, green, brown, bottle, jar, danger, Gives Isaac an eye companion that floats around the room and deals 8 damage per tick on contact with enemies, Damage from Isaac's left eye deal roughly +35% damage, * item room, treasure room, item room pool, red, white, When you take damage, this item recharges one room's worth of charge to your spacebar item, For example, with the D6 you would need to take damage 6 times to fully recharge it, * angel room pool, god room pool, angel room item, shop room pool, shop item pool, This will heal red hearts and then give soul hearts up to a total of 6. increased tears stat does not reduce the charge up time of Brimstone. These ticks occur every 1/15th of a second (once every 4 frames). syringe, needle, injection, purple, grey, gray, Causes Isaac to shrink in size (including hitbox slightly), Can be dropped when exploding mushrooms in the environment that are usually found in the Caves/Catacombs and in secret rooms, * item room, treasure room, item room pool, mushroom, blue, spotted, Adds several instances of The Bible item into all item pools. with a Brimstone Curse which makes them more vulnerable to Brimstone attacks and causes them to explode when killed by Brimstone - Tainted Eve's clots are no longer lost when recalled by Sumptorium if she has full health, instead they will drop to the . Based on the Steam Workshop mod created by Eufuu, UNLOCK: Unlock this trinket by having a lot of blue flies at once, While held this trinket gives your familiars homing shots, Added as part of the Afterbirth+ Booster Pack #5. Mini-bosses and bosses create 2-3 souls, When activated, the urn can be fired as a high damage flamethrower in any direction, A charge is consumed roughly every 0.5 seconds of use, Multi-part enemies such as Envy or Teratoma create a soul per each part killed, A maximum of 20 souls can be held in the urn at one time, UNLOCK: Unlock this item by beating Satan as Bethany, With each shot fired, another bloody tear will spawn behind Isaac, Spawning multiple tears will form a trail of tears that follow Isaac as he moves, bursting and dealing damage upon contact with enemies, The effect from this item will only work while in a hostile room that contains at least 1 enemy, UNLOCK: Unlock this item by defeating Mother in the Corpse II as Judas, Upon use, this item consumes 1 heart container or 2 soul hearts and spawns one item pedestal from the current room's pool, Every use gives a broken heart, meaning that slot is permanently broken and the maximum health limit is reduced by 1 for the rest of the run, If Isaac has 12 broken hearts, he dies instantly (this also applies to The Lost despite having no health), Magic Skin will continue to appear after finding it once if you are not still holding it - the chance for it to replace an item is 1 (12 - number of times used) up to a maximum of 50%, Broken hearts are empty heart containers that cannot be removed or refilled and will override other types of hearts when you reach 12 total. Spawns another Vurp! This makes damage per second drop to 80%. Cosmetic change only. Manage all your favorite fandoms in one place! They also retain most of your bomb synergizing items, This item causes your bombs to stick to enemies and when exploding will leave white creep on the ground which slows enemies, When one of your bombs kills an enemy, a bunch of blue spiders are spawned to fight by your side, which deal x2 your current damage, Item Pool: Item Room, Greed Mode Item Room, Bomb Beggar, Bomb Beggar, Shooting in one direction increases your fire rate until a cap is reached, The maximum effect is to halve your delay, which takes roughly 10 seconds to achieve, The accuracy of your tears is also reduced as your fire rate increases, As soon as you change firing direction, your fire rate is reset to its normal amount, Tears will now travel through walls and appear out of the opposite wall, similar to a portal-type mechanic, Your tears can now also travel over rocks and objects in the environment, Spawns 3 random types of hearts on the floor, *, pink, blonde, yellow, red, bow, baby mr dolly, Causes Isaac to spawn 6 troll bombs on the floor every time he gets hit, similar to the Anarchist Cookbook mechanic, Doesn't trigger on damage taken from blood donation machines and devil beggars (but still triggers on other forms of intentional self damage such as IV Bag), Item Pool: Item Room, Red Chest, Curse Room, Greed Mode Item Room, *, blue, orange, poster, torn, paper, page, ripped, A familiar baby that has a random chance to drop a battery pickup or freeze all enemies in the room for a short while, Charged Baby also has a chance to add one charge to your spacebar item, These effects can only occur while in a hostile room with enemies, Gives Isaac a +25% damage up for every tear that successfully hits an enemy, The bonus from Dead Eye maxes out at double your damage (+100%), If a tear misses an enemy, there is a chance for the multiplier to be reset back to 1. Frozen enemies can be pushed into obstacles where they shatter on contact and fire ice shards around them. Only stat effects are applied; otherwise overridden by Brimstone: PC 39W8 NGWZ (Red Chest on Curse Room adjacent to spawn) purple, An orbiting fly which deals 2 contact damage per tick to enemies, * item room, treasure room, item room pool, blue, Has a chance to drop from the Super Gluttony miniboss fight, Item Pool: Item Room, Super Gluttony Miniboss, * item room, treasure room, item room pool, the lost item pool, white, grey, gray, tub, Allows Isaac to fly while the Pony is held, Sets your speed stat to 1.5 if it isn't already that high, When the active attack is used, Isaac will dash across the screen dealing scaling contact damage to anything he hits, Drops from the Headless Horseman boss fight, REPENTANCE - A Pony's charge time has been reduced to 2 (from 4). Cain no puede disparar lgrimas . When used in the backwards path after picking up Dad's Note, R key will skip you to the Basement 1 version of this path, which leads directly to the Home floor. Increases the maximum heart limit to 18. ?, Satan and The Lamb as Tainted Lilith, All shops only sell familiars while holding this trinket, If you enter a shop while holding this trinket, the effect won't undo by dropping it until you move to a new floor, UNLOCK: Unlock this trinket by defeating Mother as Tainted Lilith, Every time an enemy dies you have a chance to gain a random Locust, Different color Locusts correspond to the horsemen. Collection Grid REPENTANCE - The Nail's temporary damage bonus has been increased, and is now able to stack with itself. Platelets travel to the site of the injury. Aries, Cancer, Capricorn, Leo etc.). Reveals the location of one secret room on the minimap. Also got libra but just a basic all stats up. Only contact poison has this effect - poison from tears doesn't work, UNLOCK: Unlock this item by beating Satan with Lilith, *, green, lips, kiss, drip, drop, serpents kiss, serpent kiss, Isaac will now fire tears automatically directed at a red target on the ground which is controlled by the player, This allows for a full 360 degree tear firing radius, Can be overridden by other tear modifiers such as Mom's Knife or Brimstone, Every time you leave the room this effect turns off until you press a shoot button again, Tears are replaced with the ability to charge and fire a laser ring that travels across the room, The size of the ring will depend on how long you charge it, The laser ring does damage scaling based on charge, from 25% at minimum to 100% at max, Rings have infinite range and travel until they hit a wall, Multiple Tech X stacks - every one taken adds another laser ring (doesn't affect your fire rate), * tech 10, tech ten, donut laser rings, vr, headset, visor, Allows you to create one brown tunnel and one blue tunnel in the floor, that can be used to teleport between wherever you placed each one, This item will let you port out of the devil room but not back into it, Very useful in the boss rush and challenge rooms, *, scalpel, red, silver, white, grey, gray, metal, knife, cut, Isaac's tears now travel directly forwards following a beam of light, but will also move sideways based on your player movement, Allows for more accurate correction when firing tears, as their direction can be controlled even after they have been fired, If you switch the direction in which you are firing tears, the beam of light and all your tears will also be transported to the new direction, Tears now have a random chance to apply a shrinking effect, causing enemies to shrink in size for 5 seconds and also run away from Isaac, Shrunk enemies can be crushed and killed by walking over them, After firing tears for 3 seconds, a red cross appears on Isaac's head that, upon releasing the fire button, creates a black ring which deals a lot of damage to any enemies inside it, The ring deals damage equal to your tear damage rapidly to any enemies in contact with it, for a total of 30 ticks of damage, You have to keep the fire button held down for the full 3 seconds to cause this effect, UNLOCK: Unlock this item by beating Blue Womb (Hush) with Azazel, In addition to tears, Isaac now holds a spear infront of him which deals damage equal to 2 times your tear damage. Can be used with Placebo to generate infinite batteries, Amnesia - Hides the floor map for the rest of the current floor (same as curse of the lost). Lil Clot will persist after the trinket is dropped, but it will not respawn unless the trinket is picked up again. UNLOCK: Unlock this trinket by defeating Greedier Mode with ??? in The Chest floor as The Forgotten, Item Pool: Item Room, Greed Mode item Room, When picked up, this item replaces all of your red heart containers with 6 Bone Hearts, Every time you lose a bone heart, lots of bones fire in all directions damaging any enemies hit and you gain a permanent +0.5 Tears Up, For the Lost and Keeper characters, this item simply gives a permanent Tears Up, UNLOCK: Unlock this item by defeating The Lamb in the Dark Room floor as The Forgotten, Obtained by beating the Basement 1 boss within 1 minute, then bombing the large shadow that appears in the middle of the starting room, While held, Mom's Foot will stomp on you from above twice every few seconds, and she will continue to stomp for as long as you hold this item, Using the Broken Shovel will stop Mom stomping you for the rest of the current room (or current wave if you're in the boss rush or challenge room), Beating the Boss Rush while holding this item will drop the second half of the Broken Shovel, which combine to create Mom's Shovel, which is used to unlock The Forgotten character, Dropping the Broken Shovel will cause it to disappear if you leave the room, NOTE: This item will not drop unless you have beaten The Lamb at least once, Added as part of the Afterbirth+ Booster Pack #5 and used in the quest to unlock The Forgotten character, Drops after beating the Boss Rush while holding the other half of the Broken Shovel (see previous item for more details), Combines with the first Broken Shovel piece to create Mom's Shovel (see next item for more details), When used, spawns a trapdoor that leads to the next floor, Unlocks The Forgotten character when used on a mound of dirt that appears in a room in The Dark Room floor, Obtained by combining the two Broken Shovel pieces. Seeds . Will take red hearts first before any other, Eve starts with this item after donating 439 coins to the Greed Donation Machine, UNLOCK: Unlock this item by beating Satan with Eve, Item Pool: Item Room, Curse Room, Demon Beggar, * devil pool, devil room pool, devil deal, the lost item pool, starting, silver, grey, gray, Upon use, this item refreshes the current floor with brand new rooms, monsters and items, as if you had entered a new floor, UNLOCK: Unlock this item by beating Satan with Blue Baby, Item Pool: Item Room, Secret Room, Devil Room, Demon Beggar, * secret room pool, item room, treasure room, item room pool, pill, tablet, drug, white, Counts as 1 of 3 spider items needed towards the Spider Baby transformation. Deals 200 damage to nearby enemies when reviving, Tainted Lilith - All familiars now attach to her Umbilical cord like the Gello item, Tainted Keeper - Nearby coins dropped by enemies move towards you quickly, Tainted Apollyon - Holding the fire button causes locusts to stay near enemies and damage them instead of returning, Tainted Forgotten - Grants the Recall ability. Isaac appears demonic with large curved horns and an angry expression. Deals 45 damage to enemies it lands on. Seeds UNLOCK: Unlock this item by defeating Hush as Bethany, At the beginning of each new floor, this item will stab Isaac and reduce your red health down as much as it can without killing you. or Satan), The Wafer becomes most effective in the Womb and beyond where enemies all deal a whole heart of damage, The Wafer causes the Sharp Plug item to only cost 1/2 a heart per use, Has no effect with the Keeper - there's no such thing as half a coin health point, * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, When the charge bar gets to zero it will grant you a brief period of invincibility, If the spacebar is held for too long (about 1 second) when it has no charge, you will take damage, During the invincibility period, Isaac deals 3.5 contact damage to enemies and beams of light will strike down from the sky, dealing 15 damage, If damage is blocked perfectly at the exact second the charge bar reaches zero, it will release holy beams in four directions and grant a brief shile effect, The invincibility effect is shown via a rapid flashing animation, * angel room pool, god room pool, angel room item, white, blue, ball, circle, After taking damage, if you have half a red heart or less, The Polaroid will give you an invincibility shield for 5 seconds, Allows you to open the door at the beginning of Depths II that leads to the Mausoluem, When unlocked, is guaranteed to drop after the Mom's Foot boss fight, The Polaroid will always spawn on the left pedestal, UNLOCK: Unlock this item by beating Isaac in the Cathedral 5 times, After taking damage, if you have half a red heart or less, The Negative will deal 40 damage to all enemies in the room, The Negative will always spawn on the right pedestal, UNLOCK: Unlock this item by beating Satan in Sheol 5 times, * mom's foot, mom fight, mom boss, dark room, photo, family, kodak, inverted, You no longer shoot tears and instead now control a single large tear with the arrow keys, Items which increase your tears stat will cause the tear to deal damage at a faster rate, Items which increase your shot speed cause the tear to travel faster across the screen, Ludo and Brimstone create a large controllable red ring of death that does massive damage to anything in its path, Taking this with Mom's Knife allows you to remote control the knife around the room, dealing huge damage, * item room, treasure room, item room pool, eye, pink, grey, gray, robot, REPENTANCE - Soy Milk tears now cause drastically less knockback, * item room, treasure room, item room pool, white, glass, square, Isaac's tears become homing and have an aura around them, which will deal a flat 2 damage per tick to anything inside its radius, Multiple GodHeads doesn't stack the aura damage, UNLOCK: Unlock this item by completing all post-it note marks in hard mode with The Lost character, * angel room pool, god room pool, angel room item, yellow, blue, red, triangle, all seeing eye, Gives Isaac an extra life on death, exactly the same as Lazarus' default respawn effect, When you die with this item, you respawn in the same room with 1 heart and the Anemic item, The game considers you to be a different character (Lazarus II) when this effect activates, UNLOCK: Unlock this item by beating the Isaac boss with Lazarus, * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, ), UNLOCK: Unlock this item by beating Blue Womb (Hush) with Cain, Gives Isaac a familiar golden Censer which creates a huge aura of light that slows down any enemies inside it, UNLOCK: Unlock this item by beating Greed Mode with Maggy, A familiar beggar similar to Bum Friend that follows Isaac and collects keys, giving random chests in return, UNLOCK: Unlock this item by beating Greed Mode with Lazarus, Item Pool: Item Room, Secret Room, Key Beggar, *, grey, gray, black, face, stone, rock, baby, A bag that follows Isaac and drops a random Rune or Soul Stone every 7 or 8 rooms, UNLOCK: Unlock this item by beating the Isaac boss with Lilith, A familiar angel which follows Isaac and fires Sacred Heart tears which deal 10 damage at -25% shot speed and a reduced fire rate, Item Pool: Item Room, Angel Room, Greed Mode Angel Room, This item causes enemy projectiles to be able to hit other enemies. PC 4AA3 QSMJ (Treasure Room adjacent to spawn), PC S9CH XAMT (Treasure Room adjacent to spawn), PS4 VXMQ Y96F (First Treasure Room adjacent to spawn), Achievements Each tick of poison damage is equal to your normal tear damage, Some random tears will gain the Rubber Cement effect and become bouncy, Grants +0.25 Speed, +0.75 Range, +0.1 Shot Speed, +0.2 Tears, +0.5 Damage and +1 Luck when Isaac's active item is fully charged, Infinite use items such as Potato Peeler count as charged and provide the bonus from this trinket, Grants +0.5 Speed, +1.5 Range, +0.3 Shot Speed, +0.4 Tears, +1.5 Damage when Isaac's active item is completely uncharged, One-time use items such as Mama Mega count as uncharged and provide the bonus from this trinket, Gives you another secret room on each new floor while held, Does not spawn more than one super secret room, only the normal secret room, *, purple, torn, ripped, paper, page, poster, When you have the same amount of coins, bombs and keys, half consumables turn into their doubled version, This effect works for any number of consumables, including 0 and 99, as long as the count for coins/keys/bombs is equal, Every time you take damage you have a very small chance to spawn a random pedestal item, When the effect triggers, the trinket is destroyed, Every time you take damage you have a very small chance to spawn the Lunch item, which gives +1 HP up, When the effect triggers, this trinket is destroyed, Increases the radius of any creep you produce, While held, any damage taken remove red hearts first, before soul hearts, black hearts and rotten heart damage, While at 1/2 of a red heart, it will begin to remove your other hearts again, UNLOCK: Unlock this item by beating Greedier mode with Eve, The Walnut has a chance to break when taking damage from an explosion. Rotten Baby becomes larger . Tear Appearance The damage bonus is unaffected by both positive and negative damage multipliers. . The charge direction now allows for a minor amount of control, * headless horseman, headless horsemen, red, grey, gray, A bag of bombs that will drop a bomb pickup every 2 rooms, UNLOCK: Unlock this item by beating Satan with Cain, * boss rush pool, boss rush room, secret room pool, item room, treasure room, item room pool, Kills poop bosses when used - Dingle, Dangle and Brownie, * item room, treasure room, item room pool, silver spoon handle, grey, gray, white, toilet. ?, Satan and The Lamb as Tainted Isaac, Every time you enter a brand new room, you have a chance to get a random one-time use Dice (e.g. He won't respawn even if you move to a new floor, Will always match your current movement speed, UNLOCK: Unlock this item by defeating The Beast as Tainted Keeper, Only found in the Mausoleum/Gehenna II boss room, The item itself has no effect, but triggers the ascent through the backwards path towards the Home floor. It also changes tears to a chargeable laser that pierces all objects in its path (including enemies, environmental hazards and walls). Trinkets Attributes No longer drops black hearts like it used to. Your doctor will likely perform a physical examination, and you may undergo a venous . Kicking a frozen enemy will push it into the wall, where it shatters and fires ice shards everywhere (these can then freeze other enemies), Enemies touching the cube while it's not moving or moving slowly will become slowed for a few seconds, and take a small amount of damage, Cube Baby and enemies frozen will block enemy shots, Cube Baby can be launched across the room if you have a melee weapon, Enemies that die now spawn a red ghost, that floats in place of where the enemy died, Activating the item causes all red ghosts in the room to explode, dealing damage to any enemies near them, The explosion doesn't deal damage to Isaac, Damage dealt by each ghost is 3 + 0.04x the HP of the enemy it spawned from, Larger enemies such as minibosses will spawn a larger red ghost that causes 3 explosions, The red ghosts can be moved around slightly by firing tears through them, Using the item will instantly kill any enemy or boss that has the 'ghost' tag and is at 50% or less HP. 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